SummaryThe Systems Onco-Immunology Lab (SOIL -https://www.bcm.edu/departments/surgery/surgical-research/systems-onco-immunology-lab)in the Michael E. DeBakey Department of Surgery is seeking anenthusiastic scientist to undertake research projects in the fieldof tumor immunology and immunotherapy. The research will focus onthoracic malignancies including lung cancer and malignant pleuralmesothelioma to identify and develop novel therapeutic approachesfor these malignancies. Both human tissue samples and sophisticatedanimal models will be utilized and analyzed using the most advancedtechnologies. The scientist will work under the general guidance ofa principal investigator but will be anticipated to plan andimplement experiments and analyze their results independently.Prior experience in the field of immunology is highly desiredthough not mandatory.The research focuses on thoracic malignancies including lung cancerand malignant pleural mesothelioma to identifypredictive/prognostic biomarkers and develop novel therapeuticapproaches for clinical trials. Both human tissue samples andsophisticated animal models are utilized and analyzed using themost advanced single-cell technologies including time-of-flightmass cytometry and imaging mass cytometry. Therefore, the mostessential work of this position is to 1) design, organize, perform,and analyze preclinical in vivo experiments using various mousemodels and 2) harvest, collect, and utilize experimentalspecimens.Job DutiesThe special responsibilities of research assistants in our labinclude: Setting and performing in vivo mouse experiments.Managing animal facility.Organizing experimental schedules.Collecting human and mice tissues with single cellpreparations.Creating and reviewing procedures.Managing the safety in the lab.Modifying and upgrading the experiments planned.Writing and revising animal protocols for IRB approval.Ordering lab items, including mice.Managing transfers and activities in collaboration with otherlabs.Using and arranging core labs for immunohistochemistry, flowcytometry, time-of-flight mass cytometry, imaging mass cytometry,DNA and RNA sequencing, mass spectrometry, and so on.Checking all equipment in the lab regularly.Managing cryotanks and refrigerators. Baylor College of Medicine is an Equal Opportunity/AffirmativeAction/Equal Access Employer.6369CA; CH Preferred QualificationsMaster’s degree in a related field. Minimum QualificationsBachelor’s degree in a Basic Science or a related field.Three years of relevant experience.
New justice minister Jeremy Wright today said the government would cancel plans for weekend court hearings if the trial proves to be unsuccessful. Wright, in his first public speech since joining the department last month, said it would be ‘crazy’ to pursue the policy nationwide if concerns raised by the profession about the ongoing regional tests proved to be correct. The former criminal barrister told a fringe meeting of the Conservative Party conference that he had met the Bar Council this morning to hear its view that weekend and evening sittings at court would not succeed. But Wright urged sceptics to give the pilot a chance before dismissing it, and said his own experience of the court system had convinced him improvements were necessary and possible. ‘I understand the concerns about weekend courts. Lots of cases won’t work in the evening or weekends but others will. Witnesses have to take several days of time out of work to sit around in a court building only to be called at the end of day three. ‘Asking them to go in on a Saturday might be an advantage to them. We will not be expecting [lawyers] to come in routinely on Sunday mornings but there may be a case for being a little more flexible about what hours we work,’ he said. The minister outlined a number of other efficiency savings he would to introduce in the court process, including reducing the number of papers and calling witnesses – especially police officers – and defendants by video link-up where appropriate. Wright, whose portfolio includes prisons, said the Ministry of Justice was committed to 23% savings on its budget – around £2bn – every year until 2015. The Gazette understands that Chancery Lane has been told that participating courts will choose from a ‘menu of options’, including extended court sittings on weekdays and Saturday afternoons, Sunday court sittings and extended use of virtual courts and video links to prisons. The Law Society, which opposes the scheme, said: ‘It is inappropriate for the courts to sit outside normal business hours and to require solicitors to attend weekend hearings, where there is no emergency and the cases are not of the sort usually undertaken at weekend sittings.’ It said the initiative will increase costs to law firms and ‘will be an expensive way of making the magistrates’ courts less efficient, at a time of decreasing workloads and when all the criminal justice agencies are struggling with budget cuts.’ The Society said it plans to monitor the pilots and gather evidence from solicitors about the problems caused and costs incurred, which it will share with the MoJ when it evaluates the pilots in the new year. Wright denied the MoJ’s savings plans would mean a cap on prisoner numbers and said it was a matter for the courts, rather than ministers, to decide who would go to prison. He did reveal that he would not support any reduction in the number of short sentences passed by magistrates and judges, despite criticism that they offer no rehabilitation to the offender. ‘Short prison sentences do work for public protection,’ he added. ‘There’s no doubt that the reoffending rates for short term sentences is pretty horrendous, but I am not of the view that all those who would have received a short sentence shouldn’t have one.’ Wright said that those expecting immediate reform of the probation and prison service would have to wait. Four new ministers were appointed to the department in David Cameron’s reshuffle last month and Wright said they needed to ‘pause for breath’ before introducing any new legislation.
The current Jamaican anti-Carifta Games sentiment isn’t new. Jamaica is so dominant at the 48-year-old track and field junior event that some fans might just be bored. Add the tight schedule between the ISSA/GraceKennedy Boys and Girls’ Athletics Championships and the Carifta Trials and between the Games themselves and the Penn Relays this year, and the discontent has been aggravated. However, the Games still play an important role. It is the first opportunity for young Jamaican athletes to experience international competition. The Carifta experience takes them out of familiar surroundings to other countries via air travel, and out of their school teams into a national team. It builds loyalty to the black-green-and-gold. Just as importantly, it simulates what they will experience at the highest level of the sport. EMULATE CARIFTA There’s nothing else quite like it. In fact, international officials, including IAAF President Sebastian Coe, have urged other regions to copy it. Take the Carifta Games off the calendar and you find there isn’t anything else that plays the experience-building role for the youngest ones. Every two years, the Caribbean Union of Teachers stages a 15 and under event. In 2017, the IAAF staged the last World Under 18-Championships in Nairobi, Kenya. That’s where Wayne Pinnock of Kingston College rededicated himself to athletics. Now, he is one of the globe’s pre-eminent long jump prospects. The landscape also features the Youth Olympics and the Commonwealth Youth Games, which cater to athletes under 18 years of age. However, these wonderful events are often staged so late in the year that rest for the youngsters is compromised. This was the case with the 2018 Youth Olympics in Buenos Aires, Argentina, which took place in October. The remainder of the international junior calendar caters to athletes from age 16 to 19. That bars the terrific Clayton twins, Tina and Tia, from competing at this year’s Pan-American Junior Championships. Believe it or not, Tia and Tina are just 14. Many of the region’s greats, including Usain Bolt, Veronica Campbell-Brown, Yohan Blake and Melaine Walker, benefited from exposure at Carifta and the World Under-18 Championships. Now that the latter meet is off the schedule, Carifta is a little bit more crucial. One guess about Asafa Powell’s disappointing 2004 Olympic 100-metre showing is that he lacked experience on the international stage. Discovered as a diamond in the rough, Powell missed the ladder of junior meets that moulded his peers. Perhaps, if the former footballer had turned to track earlier and gotten experience at the Carifta Games, his 2004 Olympic debut might have had a happy ending. Thankfully, he matured, brought the 100-metre world record to Jamaica, and became a three-time Olympic 100-metre finalist and a winner of individual medals at two World Championships. In the same way, the Penn Relays helps by confronting our young athletes with the vagaries of weather. At the 2017 World Championships, a strong Jamaican team was undone by the London chill. Bolt went down, baton in hand, in the 4x100m final. Anniesha McLaughlin-Whilby suffered the same way in the women’s 4x400m final. Ronald Levy pulled just before his 110-metre hurdles heat. Blake couldn’t run flat out in the 200 metres because of the 13-degree weather and the risk of injury. Lest we forget, Jamaica’s only gold medal came from hurdler supreme Omar McLeod, who is accustomed to cold weather from his ongoing sojourn in the United States. In addition, Penn Relays often sees non-stars get college scholarships. The underlying point is that Carifta and Penn still are helpful to the Jamaican track and field effort. We remove them at our peril. Hubert Lawrence is a well-respected international track and field analyst and commentator.
Cristiano Ronaldo wants to leave Juventus. His agent Jorge Mendes is looking for a new team of the Portuguese star. This is what the authoritative Spanish journalist Guillaume Balage claims. He explained that the Bianconeri are willing to sell Ronaldo to part with his huge salary.“The reason for Cristiano Ronaldo to be associated with PSG is not because the French club is thinking about attracting him, but because Jorge Mendes has been instructed to find a new team for Ronaldo. It is offered everywhere, including Barcelona. I’m not sure they can get rid of him easily because of the money he gets. Who is willing to pay such a sum? Balage told the BBC.Stoichkov: There are much better players than Cristiano Ronaldo“Paulo Dybala, for example!”
Ravens offensive coordinator Jim Caldwell accepted the Detroit Lions’ head coaching position Tuesday, officially filling the vacancy left after the Lions fired Jim Schwartz (Mount St. Joe) at the conclusion of the 2013 regular season.After San Diego Chargers offensive coordinator Ken Whisenhunt agreed to become the head coach of the Tennessee Titans earlier in the day, the Lions reportedly turned their attention to Caldwell, who interviewed for their vacancy earlier this month. He also interviewed for head coach openings with Washington and Tennessee, positions that have since been filled.The former Indianapolis Colts head coach received much praise for the job he did with the Baltimore offense in helping the Ravens win Super Bowl XLVII after being promoted from quarterbacks coach to offensive coordinator on Dec. 10, 2012. However, his offense struggled mightily in 2013 as the Ravens finished 29th in total yards and 25th in points scored while also setting franchise lows in rushing yards and yards per carry.Some had called for a change at offensive coordinator after the Ravens’ immense struggles on that side of the ball, but Caldwell’s track record in Indianapolis as well as his work late in the 2012 season make him a viable candidate for another head coaching opportunity. The Ravens were mum on Caldwell’s status for the 2014 season to avoid compromising his chances to obtain a head coach position.It remains to be seen who among the Ravens’ assistant coaches might be joining Caldwell in Detroit, but secondary coach Teryl Austin is expected to become the Lions’ new defensive coordinator. Other names rumored to potentially join Caldwell on the Lions staff are former running backs coach Wilbert Montgomery and offensive line coach Andy Moeller, whose future remains in limbo after last week’s announcement that run-game coordinator Juan Castillo would remain with the Ravens under Moeller’s title of offensive line coach.The most logical in-house candidate to replace Caldwell as offensive coordinator would be wide receivers coach Jim Hostler, who served as San Francisco’s offensive coordinator in 2007. However, the Ravens are likely to seriously explore options outside the organization to jump-start an offense expected to receive a significant facelift this offseason.Preliminary names that could be considered for the position include former Browns head coach Rob Chudzinski, Browns offensive coordinator Norv Turner, and former Vikings head coach Brad Childress.